The day after soon-to-be valedictorian Henry Burke (Matt Bush) takes a hit of the chronic for the first time, his school principal (Michael Chiklis) institutes a zero tolerance drug policy and administers a mandatory drug test for all students. Henry has two options: fail and lose his college scholarship, or team up with his stoner friend Breaux (Sean Marquette) to beat the system. They steal a high powered ganja from law student-turned-drug-dealer Psycho Ed (Adrien Brody) and spike the school's bake sale brownies, getting the whole school--faculty included--completely stoned out of their minds. But with the student body getting higher and higher with every brownie, and a pissed-off Psycho Ed on their tails for stealing his stash, they must find a way to keep their half-baked plan from going up in smoke.