We use math every day to predict weather, tell time and handle money... and two brilliant brothers use it to solve crime. When cases defy ordinary solutions, dedicated FBI agent Don Eppes (Rob Morrow) turns to his younger sibling, Professor Charlie Eppes (David Krumholtz), a mathematical prodigy. Don's unstoppable crime-fi ghting squad includes David Sinclair (Alimi Ballard), Colby Granger (Dylan Bruno), Megan Reeves (Diane Farr), and Nikki Betancourt (Sophina Brown). When the calculations become challenging, Charlie reaches out to his colleagues, theoretical physicist Larry Fleinhardt (Peter MacNicol) and computational mathematician Amita Ramanujan (Navi Rawat). At home, both brothers rely on the advice of their father Alan (Judd Hirsch).